Selective Silencing of Angiotensin Receptor Subtype 1a (AT 1a R) by RNA Interference
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چکیده
منابع مشابه
Selective silencing of angiotensin receptor subtype 1a (AT1aR) by RNA interference.
Angiotensin II exerts its physiological effects by activating multiple subtypes of its receptor such as AT1a-, AT1b-, and AT2-receptors. Because of a high degree of similarity among these G-protein-coupled receptors, it has been difficult to assign diverse physiological actions of angiotensin II through these receptor subtypes. We have developed small interfering RNAs to selectively inhibit the...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2005
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000150161.78556.c6